| A. Jesse Jiryu Davis | — | Speaker | Don't Quit, Rotate | — |
| Adam Taylor | — | Speaker | PYNQ the coolest Python Framework you never heard of. | — |
| Alexandra Sunderland | — | Speaker | From 0 to 60 in 2,592,000 seconds: How to quickly get engineers up to speed | Video |
| Aly Sivji | — | Speaker | If Statements are a Code Smell | Video |
| Andrew Godwin | — | Speaker | The RFIDiculous Inventory | — |
| Andrew Knight | — | Speaker | East Meets West When Translating Django Apps | Video |
| Anthony Shaw | — | Speaker | Why is Python slow? | Video |
| Ariane Camilo Pinheiro Alves | — | Speaker | Fighting misuse of public funds one tweet at a time | — |
| Benjamin Bengfort | — | Speaker | Democratic APIs: Balancing Hierarchy and Humanity in Pythonic Interface Design | — |
| Benjamin Bengfort | — | Speaker | Monitoring the Power Grid with Python | — |
| Benjamin Peterson | — | Speaker | Python 2.7: A retrospective | — |
| Brian Grohe | — | Speaker | Automated tests running too slow? Time to investigate. | — |
| Brian K Okken | — | Speaker | Multiply your Testing Effectiveness with Parameterized Testing | Video |
| Calvin Hendryx-Parker | — | Speaker | Finite State Machine (FSM) in Django | Video |
| Carol J. Smith | — | Speaker | Implementing Ethics: Developing Trustworthy AI | Video |
| Casey Faist | — | Speaker | Lessons in Legacy | — |
| Catherine Nelson | — | Speaker | Practical privacy-preserving machine learning in Python | Video |
| Chris Seto | — | Speaker | Big O No: Django ORM runtime complexity and how to avoid it using LATERAL JOINS | Video |
| Colin Carroll | — | Speaker | Getting started with automatic differentiation | Video |
| Conor Hoekstra | — | Speaker | Beautiful Python Refactoring | Video |
| Cristina Muñoz | — | Speaker | Detección automatizada de archivos maliciosos en el repositorio PyPI | Video |
| Dan Petro | — | Speaker | How Real-world Python Applications Get Compromised | — |
| Daniel Imberman | — | Speaker | Life Beyond Yaml: Bridging Data Science and Data Infrastructure with Apache Airflow | Video |
| David Mauricio Delgado Ruiz | — | Speaker | Datos, Python y humanos: haciendo ciencia de datos en países latinoamericanos | Video |
| Dean Wampler | — | Speaker | Ray: A System for High-performance, Distributed Python Applications | Video |
| Débora Azevedo | — | Speaker | How PyLadies Brazil became the biggest PyLadies chapter of the world | — |
| Deepak Kumar Gupta | — | Speaker | Saved by In-Memory NoSQL - A hitchhiker guided to Black Box debugging of Python Production Code | Video |
| Denny Perez | — | Speaker | Diario de mi transición personal y profesional: como la comunidad de Python me inspiró | — |
| Dharhas Pothina | — | Speaker | Analyzing 200 billion GPS Points with Python on the Cheap | — |
| Dino Mintas | — | Speaker | Lessons Learned from Scaling Up a Django Project | — |
| Dmitry Figol | — | Speaker | Managing Python dependencies with Poetry | — |
| Dr. Cristián Maureira-Fredes | — | Speaker | C++ ♥ Python: from modules to hybrid applications | Video |
| Dustin Ingram | — | Speaker | Static Typing in Python | Video |
| Eduardo Vicente Gonçalves | — | Speaker | Fighting misuse of public funds one tweet at a time | — |
| Elaine Wong | — | Speaker | 9 Years of PyLadies: Lessons Learned and What Comes Next | Video |
| Elizaveta Shashkova | — | Speaker | The Hidden Power of the Python Runtime | Video |
| Émilie Feral | — | Speaker | Teaching Python to a whole country | — |
| Emmanuelle Gouillart | — | Speaker | Building interactive applications for image data with Dash and scikit-image | Video |
| Eric J. Ma | — | Speaker | A careful walk through probability distributions, using Python | Video |
| Eric Nahuel Horvat | — | Speaker | Integraciones con Asyncio | Video |
| Flávio Juvenal da Silva Junior | — | Speaker | 1 + 1 = 1 or Record Deduplication with Python | Video |
| Fred Phillips | — | Speaker | Hooking into the Python import system | — |
| Hank Preston | — | Speaker | Introduction to Writing Network Tests with pyATS | Video |
| Hannah Stepanek | — | Speaker | Let's talk Databases in Python: SQLAlchemy and Alembic | Video |
| Harry Percival | — | Speaker | Stop Using Mocks (for a while) | Video |
| Igor T. Ghisi | — | Speaker | Write Less and Test More with Data Regression Testing | Video |
| Itamar Turner-Trauring | — | Speaker | Small Big Data: using NumPy and Pandas when your data doesn't fit in memory | Video |
| J. Weissbock | — | Speaker | Distributed Web Scraping in Python | — |
| James Bennett | — | Speaker | A 🐍's guide to Unicode | Video |
| Javier Jorge Cano | — | Speaker | “Sorry, Could you repeat that again?” - Speech Recognition with Python | Video |
| Jeff Bass | — | Speaker | Yin Yang Ranch: Building a Distributed Computer Vision Pipeline using Python, OpenCV and ZMQ | Video |
| Jessica Garson | — | Speaker | How I Solved my NYC Parking Problem with Python | Video |
| Jimmy Lai | — | Speaker | LibCST - automated code refactoring made easy | — |
| Jon Crall | — | Speaker | Developing With Doctests | Video |
| Joseph DeMesy | — | Speaker | How Real-world Python Applications Get Compromised | — |
| Jukka Lehtosalo | — | Speaker | Getting the most out of mypy and static type checking | — |
| Kas Stohr | — | Speaker | “Run All”: How to build user-friendly applications using just Python 3 and Jupyter Notebooks | — |
| Katherine Scott | — | Speaker | A Crash Course in Virtual Robotics: an Introduction to ROS 2 with Python 3 | — |
| Kathryn Lingel | — | Speaker | Pyambic Pentameter: generating rhyming and metered poems with Markov chains and NLTK | Video |
| Katie McLaughlin | — | Speaker | What is deployment, anyway? | Video |
| Kim Pevey | — | Speaker | Analyzing 200 billion GPS Points with Python on the Cheap | — |
| Kim-Adeline Miguel | — | Speaker | Decoding bias and narrative in competitive video games broadcasts with video analysis | Video |
| Léa Saviot | — | Speaker | Teaching Python to a whole country | — |
| Lennart Regebro | — | Speaker | Moving big projects to Python 3 | — |
| Lisa Guo | — | Speaker | Asyncio - liberating your compute potential and more | — |
| Lorena Mesa | — | Speaker | 9 Years of PyLadies: Lessons Learned and What Comes Next | Video |
| Luis Diego Conejo Alpizar | — | Speaker | Historias de debug en clase de Python Avanzado | Video |
| Łukasz Langa | — | Speaker | AsyncIO + Music | Video |
| Maggie Moss | — | Speaker | Gradual Typing in Practice | — |
| Manojit Nandi | — | Speaker | The Limitations and Danger of Facial Recognition | Video |
| Maria Jose Molina-Contreras, phD | — | Speaker | How to build an intelligent “indoor garden” with microcontrollers, CircuitPython, and IoT. | Video |
| Mariatta | — | Speaker | 9 Years of PyLadies: Lessons Learned and What Comes Next | Video |
| Marlene Mhangami | — | Speaker | Leadership and Identity in the Pan-African Python movement | Video |
| Mason Egger | — | Speaker | Building Docs like Code: Continuous Integration for Documentation | Video |
| Matthew Knapp Bachmann | — | Speaker | Transitioning from developing software to developing people: A firsthand experience | Video |
| Matthew Rocklin | — | Speaker | Deploying Python at Scale with Dask | Video |
| Mel Chua | — | Speaker | Mismatches and tensions: what PyPI can teach us about open source infrastructure sustainability | — |
| Michael J Haas | — | Speaker | So Long and Thanks for All the Fish: Listening to dolphins using Python and the scientific stack. | — |
| Michael Lynch | — | Speaker | How to Do Code Reviews Like a Human | — |
| Neeraj Pandey | — | Speaker | The joy of creating art with code. | Video |
| Nina Zakharenko | — | Speaker | Goodbye Print, Hello Debugger! | Video |
| Oscar Cortez | — | Speaker | Empaquetamiento en Python de manera sencilla | — |
| Pablo Galindo Salgado | — | Speaker | The soul of the beast: Everything about Python's grammar | — |
| Paul Ganssle | — | Speaker | What to do When the Bug is in Someone Else's Code | — |
| Paul Kehrer | — | Speaker | TUFening PyPI: Securing the Package Supply Chain | — |
| Peter McCormick | — | Speaker | Prototyping new Python language features in pure Python | — |
| Pratyush Das | — | Speaker | Python in High Energy Physics | Video |
| Rebeca Sarai | — | Speaker | Privacy-preserving methods: Building secure projects | Video |
| Rebecca S Bilbro | — | Speaker | Democratic APIs: Balancing Hierarchy and Humanity in Pythonic Interface Design | — |
| Rebekah Post | — | Speaker | Becoming a Polyglot: Lessons from Natural Language Learning | — |
| Renne Silva Gomes de Oliveira Rocha | — | Speaker | Si no está documentado, su proyecto no existe. | Video |
| Reuven M. Lerner | — | Speaker | Function dissection lab -- learn how functions work by examining their innards | Video |
| Richard Liaw | — | Speaker | Distributed Hyperparameter Tuning: A Guide | — |
| Robson Luis Monteiro Junior | — | Speaker | Polyglot data with python: Introducing Pandas and Apache Arrow | Video |
| Russell Keith-Magee | — | Speaker | Snakes in a case: Packaging Python apps for distribution | Video |
| Shauna Gordon-McKeon | — | Speaker | Organizing To Improve Your Workplace: Know Your Rights | Video |
| Shreya Khurana | — | Speaker | "Bonjour mademoiselle! Wie geht es dir? Wǒ hěn hǎo. Dhanyawaad" -How multilingual is your NLP model? | Video |
| Stephen Jacobs | — | Speaker | Mismatches and tensions: what PyPI can teach us about open source infrastructure sustainability | — |
| Takanori Suzuki | — | Speaker | Automate the Boring Stuff with Slackbot | Video |
| Tania Allard | — | Speaker | Docker and Python: making them play nicely and securely for Data Science and ML | Video |
| Terri Oda | — | Speaker | Using Python to Detect Vulnerabilities in Binaries | Video |
| Thea Flowers | — | Speaker | Controlling the world of modular synthesizers using CircuitPython | — |
| Tom Christie | — | Speaker | Introducing HTTPX | — |
| Tom Forbes | — | Speaker | Writing a Python autoreloader | — |
| Trey Hunner | — | Speaker | Comprehensible Comprehensions | Video |
| Tyler Potts | — | Speaker | Analyzing 200 billion GPS Points with Python on the Cheap | — |
| Valery Calderon | — | Speaker | Sacandole el maximo provecho a Pymongo | — |
| Victor Stinner | — | Speaker | Python Performance: Past, Present and Future (PyPy, Cython, C API, subinterpreters, tracing GC) | — |
| Vinayak Mehta | — | Speaker | The Hitchhiker's Guide to CLIs in Python | Video |
| Wendi Dreesen | — | Speaker | Mixing a Raspberry Pi with Python into a 5th Grade Science Fair Project | Video |
| William Woodruff | — | Speaker | TUFening PyPI: Securing the Package Supply Chain | — |
| William Woodruff | — | Speaker | Bringing Two Factor Authentication to PyPI | — |
| Yue Zhao | — | Speaker | Developing Python Libraries for Machine Learning: Best Practices and Lessons Learned | — |
| Yusuf Khan | — | Speaker | “Run All”: How to build user-friendly applications using just Python 3 and Jupyter Notebooks | — |